Best enzyme cleaner for pet urine on hardwood floors

Every enzyme cleaner we checked for hardwood

We lined up what each maker says about wood, because floor makers warn about wet cleaners.⁵

Every enzyme cleaner we checked for hardwood

Product	Type	Form	What the maker says about wood	Preservatives	Oils cats react to	Cost per oz (ready to use)	Price
Bona Pet System Floor Cleaner, Cat Formula, 32 fl oz1	Bacteria-made enzymes	Ready to use	Made for hardwood floors	Lists two isothiazolinone preservatives	None listed	$0.34 per ozas listed	$10.97
Rocco & Roxie Stain & Odor Eliminator, 1 gallon3	Bacteria and enzymes	Ready to use	Light use on wood	Not published	Lists only "Fragrance"	$0.47 per ozas listed	$59.97
Nature's Miracle Advanced Dog Stain & Odor Eliminator, 32 fl oz4	Enzyme blend	Ready to use	Not on untreated wood	Lists a preservative	Lists only "Fragrance"	$0.42 per ozas listed	$13.57
Simple Solution Hard Floor Dog Stain & Odor Remover, 32 fl oz6	Enzyme formula	Ready to use	Sealed hardwood only	Not published	Not published	$0.57 per ozas listed	$18.16

Prices on Amazon, November 2, 2026.⁷

What do floor makers say about wet cleaners and pet urine?

Mohawk's care manual for engineered wood says to remove spills promptly and not leave moisture on the floor.⁸ It says not to pour liquid directly on the floor.⁵ For spots it says to mist a clean microfiber cloth with a Mohawk recommended cleaner and rub the area.⁹

Mohawk also says damage from excessively wet maintenance, or from detergents and other cleaners, is not covered by its warranty.¹⁰ Bona says that on hardwood, using too much water or the wrong cleaning ingredients can cause damage.¹¹ Check your own floor's care sheet before you pick a cleaner.

Is an enzyme cleaner safe on hardwood?

Rocco & Roxie says its cleaner is safe and effective on many hardwood floors. It also says that too much water can cause swelling and, in extreme cases, warping.¹² Its FAQ says to use it sparingly on wood.³

Nature's Miracle says not to use its Advanced cleaner on untreated hardwood.⁴ Bona describes its cat formula as designed to clean hardwood or hard-surface floors, carpet and area rugs.¹ None of the three says raw wood is fine.

Which enzyme cleaner has a floor maker behind it?

Bona's Cat Formulation is the enzyme one. Bona says it is probiotic based and produces enzymes when a food source is present.¹ It comes ready to use, so there is nothing to mix.¹

Bona's Dog Formulation is different. Bona describes it as an oxy powered cleaner that uses hydrogen peroxide.² If you want an enzyme cleaner for dog urine, Rocco & Roxie is the alternate on this page, used sparingly.³

Questions people ask

Can I use vinegar on a hardwood floor to clean pet urine?

Bona says vinegar is an acid that can break down the finish on a hardwood floor.¹³

Can I use a steam mop on pet urine?

Mohawk's care manual says never to steam mop wood products.¹⁴

Do I spray the cleaner on the floor or on a cloth?

Mohawk's manual says to mist a clean microfiber cloth and rub the area.⁹ Bona's cat formula is sold as a spray you use on the floor or with a mop; check your floor's care sheet.¹